#Head information NAME 3ab1 TYPE alpha-beta REPRESENTATIVE 1tpv-B_77 MEMBERS 24 CLUSTER 2 #Loop element >1tpv-B_77 .........pamikdiGAAwvil... 3ab1_0.pdb 0 >1trd-B_79 .........lpilkdfGVNwivl... 3ab1_1.pdb 0 > 1igs_117 ........qiddaynlGADtvlli.. 3ab1_2.pdb 0 >2tmd-A_154 ........aakrsrdaGFDivyvyg. 3ab1_3.pdb 0 >1ubs-A_113 .......afyarceqvGVDsvlv... 3ab1_4.pdb 0 >8ruc-A_245 ........ravfarelGVPivmhd.. 3ab1_5.pdb 1 > 1cdg_215 .........ikmwldlGIDgirm... 3ab1_6.pdb 0 > 2ebn_111 ........lkntcdlyNLDgvffd.. 3ab1_7.pdb 0 >2kau-C_203 ........alreqvaaGVIglki... 3ab1_8.pdb 0 > 2aaa_191 ........vadlvsnySVDglri... 3ab1_9.pdb 0 > 1smd_182 ........ymnhlidiGVAgfri... 3ab1_10.pdb 0 >1qor-A_174 ......aqkaqsalkaGAWqvi.... 3ab1_11.pdb 0 > 1ghr_15 .....astvvsmfksnGIKsmrl... 3ab1_12.pdb 0 >1ghs-A_15 .....rsdvvqlyrskGINgmri... 3ab1_13.pdb 0 > 1edg_64 ......kqmidaikqkGFNtvri... 3ab1_14.pdb 0 > 1cdg_65 ...........yltgmGVTaiwi... 3ab1_15.pdb 0 > 1pii_265 ......gqdakaaydaGAIyggli.. 3ab1_16.pdb 0 > 1xis_35 .....pvesvrrlaelGAHgvtfh.. 3ab1_17.pdb 0 > 1amg_38 ....ilrqqaatiaadGFSaiwm... 3ab1_18.pdb 0 >1dnp-A_89 ..........qvcaenSVThlfyn.. 3ab1_19.pdb 0 >2ohx-A_226 ......kdkfakakevGATecv.... 3ab1_20.pdb 0 >1vhr-A_41 .........ipklqklGIThvln... 3ab1_21.pdb 0 > 1pbn_99 ........pvrvfrllGVEtlvvtn. 3ab1_22.pdb 0 > 3pfk_86 .........ieqlkkhGIQglvvig. 3ab1_23.pdb 0 #Motif sequence .........PAMIKDIGAAWVIL... .........LPILKDFGVNWIVL... ........QIDDAYNLGADTVLLI.. ........AAKRSRDAGFDIVYVYG. .......AFYARCEQVGVDSVLV... ........RAVFARELGVPIVMHD.. .........IKMWLDLGIDGIRM... ........LKNTCDLYNLDGVFFD.. ........ALREQVAAGVIGLKI... ........VADLVSNYSVDGLRI... ........YMNHLIDIGVAGFRI... ......AQKAQSALKAGAWQVI.... .....ASTVVSMFKSNGIKSMRL... .....RSDVVQLYRSKGINGMRI... ......KQMIDAIKQKGFNTVRI... ...........YLTGMGVTAIWI... ......GQDAKAAYDAGAIYGGLI.. .....PVESVRRLAELGAHGVTFH.. ....ILRQQAATIAADGFSAIWM... ..........QVCAENSVTHLFYN.. ......KDKFAKAKEVGATECV.... .........IPKLQKLGITHVLN... ........PVRVFRLLGVETLVVTN. .........IEQLKKHGIQGLVVIG. #Loop sequence GAA GVN GAD GFD GVD GVP GID NLD GVI SVD GVA GAW GIK GIN GFN GVT GAI GAH GFS SVT GAT GIT GVE GIQ #Fingerprint G V D : : : : : : : : : : : : : : : : : T : : : : : : : A : : : N : : : : : : : : A : : : : I I : : : : : E : : H : : K : F P S : Q : : S N L W #Geometry parameters DISTANCE 8.33 ( 0.19) Vector1 ( 0.26 -0.63 -0.73) Vector2 ( 0.18 0.93 0.31) Vector3 ( 0.07 0.27 0.96) Struc diversity(A) ( 2.1 2.3 2.5) #RMSD matrix of conformation of loops (A) 0.00 0.63 0.74 0.80 0.84 1.32 1.26 0.86 1.21 1.14 1.12 1.44 0.78 0.54 0.61 0.70 0.91 0.77 0.77 1.16 1.23 1.02 0.51 0.85 0.63 0.00 1.10 1.15 0.96 1.81 1.52 1.05 1.41 1.10 1.26 1.68 0.75 0.60 0.71 0.55 1.25 1.19 0.86 1.11 1.37 0.74 0.65 0.43 0.74 1.10 0.00 0.44 0.55 1.09 0.67 0.69 0.59 1.09 0.62 0.80 0.71 0.74 0.68 0.86 0.32 0.30 0.62 1.15 0.63 1.16 0.55 1.21 0.80 1.15 0.44 0.00 0.72 0.94 0.70 0.58 0.82 0.82 0.86 1.03 0.82 0.76 0.91 0.87 0.47 0.48 0.66 0.87 0.97 1.00 0.63 1.16 0.84 0.96 0.55 0.72 0.00 1.27 0.64 0.46 0.73 0.89 0.36 0.81 0.37 0.48 0.70 0.69 0.47 0.56 0.73 1.00 0.70 0.95 0.47 1.01 1.32 1.81 1.09 0.94 1.27 0.00 1.06 1.02 1.47 1.41 1.33 1.30 1.40 1.30 1.62 1.65 0.92 0.92 1.54 1.47 1.56 1.74 1.33 1.84 1.26 1.52 0.67 0.70 0.64 1.06 0.00 0.67 0.66 1.06 0.49 0.55 0.90 1.02 1.14 1.16 0.41 0.60 1.00 1.15 0.75 1.33 0.92 1.51 0.86 1.05 0.69 0.58 0.46 1.02 0.67 0.00 1.00 0.62 0.69 1.04 0.58 0.51 0.98 0.81 0.53 0.59 0.87 0.72 1.05 0.87 0.56 1.03 1.21 1.41 0.59 0.82 0.73 1.47 0.66 1.00 0.00 1.29 0.60 0.63 0.95 1.09 0.86 1.04 0.65 0.76 0.71 1.38 0.40 1.35 0.91 1.45 1.14 1.10 1.09 0.82 0.89 1.41 1.06 0.62 1.29 0.00 1.12 1.44 0.82 0.78 1.24 0.85 1.01 1.11 0.96 0.20 1.38 0.52 0.85 0.89 1.12 1.26 0.62 0.86 0.36 1.33 0.49 0.69 0.60 1.12 0.00 0.53 0.63 0.82 0.87 0.96 0.48 0.62 0.90 1.22 0.50 1.23 0.73 1.31 1.44 1.68 0.80 1.03 0.81 1.30 0.55 1.04 0.63 1.44 0.53 0.00 1.03 1.23 1.21 1.39 0.63 0.83 1.19 1.54 0.54 1.62 1.15 1.72 0.78 0.75 0.71 0.82 0.37 1.40 0.90 0.58 0.95 0.82 0.63 1.03 0.00 0.33 0.68 0.57 0.71 0.78 0.74 0.89 0.87 0.76 0.43 0.74 0.54 0.60 0.74 0.76 0.48 1.30 1.02 0.51 1.09 0.78 0.82 1.23 0.33 0.00 0.68 0.52 0.76 0.75 0.74 0.85 1.08 0.71 0.35 0.64 0.61 0.71 0.68 0.91 0.70 1.62 1.14 0.98 0.86 1.24 0.87 1.21 0.68 0.68 0.00 0.52 0.89 0.81 0.50 1.29 0.86 1.04 0.49 0.88 0.70 0.55 0.86 0.87 0.69 1.65 1.16 0.81 1.04 0.85 0.96 1.39 0.57 0.52 0.52 0.00 0.98 0.96 0.47 0.88 1.10 0.56 0.41 0.49 0.91 1.25 0.32 0.47 0.47 0.92 0.41 0.53 0.65 1.01 0.48 0.63 0.71 0.76 0.89 0.98 0.00 0.26 0.82 1.09 0.68 1.20 0.66 1.31 0.77 1.19 0.30 0.48 0.56 0.92 0.60 0.59 0.76 1.11 0.62 0.83 0.78 0.75 0.81 0.96 0.26 0.00 0.82 1.17 0.79 1.24 0.59 1.30 0.77 0.86 0.62 0.66 0.73 1.54 1.00 0.87 0.71 0.96 0.90 1.19 0.74 0.74 0.50 0.47 0.82 0.82 0.00 1.01 0.87 0.83 0.53 0.86 1.16 1.11 1.15 0.87 1.00 1.47 1.15 0.72 1.38 0.20 1.22 1.54 0.89 0.85 1.29 0.88 1.09 1.17 1.01 0.00 1.46 0.50 0.88 0.89 1.23 1.37 0.63 0.97 0.70 1.56 0.75 1.05 0.40 1.38 0.50 0.54 0.87 1.08 0.86 1.10 0.68 0.79 0.87 1.46 0.00 1.40 0.91 1.46 1.02 0.74 1.16 1.00 0.95 1.74 1.33 0.87 1.35 0.52 1.23 1.62 0.76 0.71 1.04 0.56 1.20 1.24 0.83 0.50 1.40 0.00 0.75 0.46 0.51 0.65 0.55 0.63 0.47 1.33 0.92 0.56 0.91 0.85 0.73 1.15 0.43 0.35 0.49 0.41 0.66 0.59 0.53 0.88 0.91 0.75 0.00 0.74 0.85 0.43 1.21 1.16 1.01 1.84 1.51 1.03 1.45 0.89 1.31 1.72 0.74 0.64 0.88 0.49 1.31 1.30 0.86 0.89 1.46 0.46 0.74 0.00 #Sequence identities difference matrix of loop (%) 0.0 67.0 33.0 67.0 67.0 67.0 67.0100.0 67.0100.0 33.0 33.0 67.0 67.0 67.0 67.0 33.0 33.0 67.0100.0 33.0 67.0 67.0 67.0 67.0 0.0 67.0 67.0 33.0 33.0 67.0100.0 33.0 67.0 33.0 67.0 67.0 33.0 33.0 33.0 67.0 67.0 67.0 67.0 67.0 67.0 33.0 67.0 33.0 67.0 0.0 33.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 67.0 67.0 33.0 33.0 67.0100.0 33.0 67.0 67.0 67.0 67.0 67.0 33.0 0.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 67.0 33.0100.0 67.0 67.0 67.0 67.0 67.0 33.0 33.0 33.0 0.0 33.0 33.0 67.0 33.0 33.0 33.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 33.0 67.0 67.0 33.0 0.0 67.0100.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 67.0 33.0 33.0 33.0 67.0 0.0 67.0 67.0 67.0 67.0 67.0 33.0 33.0 67.0 67.0 67.0 67.0 67.0100.0 67.0 33.0 67.0 33.0 100.0100.0 67.0 67.0 67.0100.0 67.0 0.0100.0 67.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0100.0 67.0 33.0 67.0 67.0 33.0 33.0 67.0100.0 0.0 67.0 33.0 67.0 67.0 67.0 67.0 33.0 33.0 67.0 67.0 67.0 67.0 67.0 33.0 67.0 100.0 67.0 67.0 67.0 33.0 67.0 67.0 67.0 67.0 0.0 67.0100.0100.0100.0100.0 67.0100.0100.0100.0 33.0100.0100.0 67.0100.0 33.0 33.0 67.0 67.0 33.0 33.0 67.0100.0 33.0 67.0 0.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 67.0 67.0 67.0 67.0 33.0 67.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0100.0 67.0100.0 67.0 0.0 67.0 67.0 67.0 67.0 33.0 33.0 67.0100.0 33.0 67.0 67.0 67.0 67.0 67.0 67.0 67.0 67.0 67.0 33.0100.0 67.0100.0 67.0 67.0 0.0 33.0 67.0 67.0 67.0 67.0 67.0100.0 67.0 33.0 67.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0 33.0100.0 67.0100.0 67.0 67.0 33.0 0.0 33.0 67.0 67.0 67.0 67.0100.0 67.0 33.0 67.0 33.0 67.0 33.0 67.0 33.0 67.0 67.0 67.0100.0 67.0100.0 67.0 67.0 67.0 33.0 0.0 67.0 67.0 67.0 33.0100.0 67.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 33.0 33.0 67.0100.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0 0.0 67.0 67.0 67.0 33.0 33.0 33.0 33.0 67.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0100.0 33.0100.0 67.0 33.0 67.0 67.0 67.0 67.0 0.0 33.0 67.0100.0 33.0 67.0 67.0 67.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0100.0 67.0100.0 67.0 33.0 67.0 67.0 67.0 67.0 33.0 0.0 67.0100.0 33.0 67.0 67.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 67.0100.0 67.0100.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 67.0 0.0100.0 67.0 67.0 67.0 67.0 100.0 67.0100.0100.0 67.0 67.0100.0100.0 67.0 33.0 67.0100.0100.0100.0100.0 33.0100.0100.0100.0 0.0 67.0 67.0 67.0100.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0100.0 67.0100.0 67.0 33.0 67.0 67.0 67.0 33.0 33.0 33.0 67.0 67.0 0.0 33.0 67.0 67.0 67.0 67.0 67.0 67.0 67.0 67.0 33.0100.0 67.0100.0 67.0 67.0 33.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0 33.0 0.0 67.0 33.0 67.0 33.0 67.0 67.0 33.0 33.0 67.0100.0 33.0 67.0 33.0 67.0 67.0 67.0 67.0 33.0 67.0 67.0 67.0 67.0 67.0 67.0 0.0 67.0 67.0 67.0 67.0 67.0 67.0 67.0 33.0100.0 67.0100.0 67.0 67.0 33.0 33.0 67.0 67.0 67.0 67.0 67.0100.0 67.0 33.0 67.0 0.0 #Sequence identities difference matrix of motif (%) 0.0 35.0 46.0 54.0 50.0 54.0 42.0 58.0 61.0 58.0 42.0 50.0 54.0 65.0 50.0 50.0 54.0 62.0 62.0 58.0 50.0 46.0 62.0 54.0 35.0 0.0 54.0 58.0 54.0 54.0 42.0 62.0 46.0 54.0 42.0 62.0 58.0 62.0 54.0 38.0 58.0 65.0 65.0 54.0 54.0 42.0 54.0 46.0 46.0 54.0 0.0 54.0 50.0 46.0 46.0 43.0 58.0 50.0 58.0 54.0 65.0 69.0 50.0 58.0 46.0 58.0 69.0 62.0 58.0 42.0 54.0 54.0 54.0 58.0 54.0 0.0 50.0 46.0 50.0 58.0 54.0 58.0 58.0 58.0 73.0 69.0 62.0 62.0 54.0 65.0 69.0 65.0 69.0 58.0 54.0 54.0 50.0 54.0 50.0 50.0 0.0 46.0 54.0 54.0 43.0 54.0 54.0 58.0 62.0 65.0 54.0 54.0 65.0 62.0 65.0 58.0 54.0 50.0 58.0 62.0 54.0 54.0 46.0 46.0 46.0 0.0 54.0 54.0 54.0 54.0 54.0 54.0 69.0 65.0 62.0 54.0 58.0 58.0 69.0 54.0 58.0 50.0 50.0 62.0 42.0 42.0 46.0 50.0 54.0 54.0 0.0 44.0 50.0 46.0 42.0 58.0 54.0 54.0 54.0 46.0 58.0 62.0 62.0 58.0 62.0 38.0 58.0 46.0 58.0 62.0 43.0 58.0 54.0 54.0 44.0 0.0 58.0 50.0 54.0 65.0 73.0 69.0 65.0 62.0 63.0 62.0 73.0 54.0 69.0 58.0 62.0 62.0 61.0 46.0 58.0 54.0 43.0 54.0 50.0 58.0 0.0 42.0 42.0 58.0 65.0 58.0 58.0 46.0 58.0 62.0 65.0 54.0 62.0 54.0 50.0 54.0 58.0 54.0 50.0 58.0 54.0 54.0 46.0 50.0 42.0 0.0 42.0 62.0 62.0 50.0 54.0 50.0 64.0 69.0 69.0 50.0 65.0 58.0 58.0 58.0 42.0 42.0 58.0 58.0 54.0 54.0 42.0 54.0 42.0 42.0 0.0 62.0 62.0 54.0 54.0 42.0 62.0 62.0 69.0 58.0 62.0 50.0 58.0 54.0 50.0 62.0 54.0 58.0 58.0 54.0 58.0 65.0 58.0 62.0 62.0 0.0 56.0 62.0 54.0 62.0 46.0 62.0 62.0 65.0 46.0 54.0 69.0 65.0 54.0 58.0 65.0 73.0 62.0 69.0 54.0 73.0 65.0 62.0 62.0 56.0 0.0 38.0 58.0 65.0 65.0 65.0 69.0 69.0 62.0 62.0 65.0 65.0 65.0 62.0 69.0 69.0 65.0 65.0 54.0 69.0 58.0 50.0 54.0 62.0 38.0 0.0 50.0 62.0 59.0 62.0 69.0 69.0 62.0 62.0 65.0 65.0 50.0 54.0 50.0 62.0 54.0 62.0 54.0 65.0 58.0 54.0 54.0 54.0 58.0 50.0 0.0 58.0 58.0 65.0 58.0 69.0 54.0 54.0 65.0 62.0 50.0 38.0 58.0 62.0 54.0 54.0 46.0 62.0 46.0 50.0 42.0 62.0 65.0 62.0 58.0 0.0 65.0 65.0 58.0 46.0 58.0 42.0 58.0 54.0 54.0 58.0 46.0 54.0 65.0 58.0 58.0 63.0 58.0 64.0 62.0 46.0 65.0 59.0 58.0 65.0 0.0 65.0 57.0 69.0 58.0 65.0 69.0 65.0 62.0 65.0 58.0 65.0 62.0 58.0 62.0 62.0 62.0 69.0 62.0 62.0 65.0 62.0 65.0 65.0 65.0 0.0 69.0 65.0 62.0 58.0 62.0 65.0 62.0 65.0 69.0 69.0 65.0 69.0 62.0 73.0 65.0 69.0 69.0 62.0 69.0 69.0 58.0 58.0 57.0 69.0 0.0 73.0 65.0 69.0 77.0 77.0 58.0 54.0 62.0 65.0 58.0 54.0 58.0 54.0 54.0 50.0 58.0 65.0 69.0 69.0 69.0 46.0 69.0 65.0 73.0 0.0 62.0 50.0 54.0 58.0 50.0 54.0 58.0 69.0 54.0 58.0 62.0 69.0 62.0 65.0 62.0 46.0 62.0 62.0 54.0 58.0 58.0 62.0 65.0 62.0 0.0 54.0 65.0 62.0 46.0 42.0 42.0 58.0 50.0 50.0 38.0 58.0 54.0 58.0 50.0 54.0 62.0 62.0 54.0 42.0 65.0 58.0 69.0 50.0 54.0 0.0 58.0 42.0 62.0 54.0 54.0 54.0 58.0 50.0 58.0 62.0 50.0 58.0 58.0 69.0 65.0 65.0 65.0 58.0 69.0 62.0 77.0 54.0 65.0 58.0 0.0 50.0 54.0 46.0 54.0 54.0 62.0 62.0 46.0 62.0 54.0 58.0 54.0 65.0 65.0 65.0 62.0 54.0 65.0 65.0 77.0 58.0 62.0 42.0 50.0 0.0 #Sequence identities difference matrix of global PDB chains (%) 0.0 50.0 82.0 87.0 79.0 86.0 88.0 81.0 87.0 86.0 86.0 84.0 80.0 80.0 83.0 88.0 84.0 82.0 85.0 84.0 83.0 82.0 84.0 84.0 50.0 0.0 82.0 89.0 82.0 85.0 88.0 84.0 87.0 85.0 87.0 83.0 83.0 84.0 83.0 88.0 85.0 85.0 86.0 86.0 83.0 83.0 83.0 85.0 82.0 82.0 0.0 88.0 81.0 85.0 89.0 84.0 89.0 87.0 85.0 82.0 85.0 83.0 83.0 89.0 81.0 84.0 85.0 87.0 86.0 86.0 82.0 84.0 87.0 89.0 88.0 0.0 86.0 83.0 84.0 89.0 82.0 85.0 80.0 85.0 87.0 87.0 85.0 84.0 85.0 83.0 83.0 85.0 84.0 91.0 88.0 85.0 79.0 82.0 81.0 86.0 0.0 84.0 88.0 81.0 85.0 86.0 87.0 80.0 83.0 81.0 84.0 88.0 84.0 82.0 80.0 83.0 85.0 84.0 78.0 81.0 86.0 85.0 85.0 83.0 84.0 0.0 84.0 84.0 83.0 84.0 82.0 82.0 85.0 83.0 84.0 84.0 82.0 82.0 83.0 81.0 82.0 86.0 83.0 80.0 88.0 88.0 89.0 84.0 88.0 84.0 0.0 85.0 81.0 79.0 81.0 87.0 87.0 86.0 85.0 0.0 84.0 83.0 84.0 83.0 86.0 90.0 85.0 85.0 81.0 84.0 84.0 89.0 81.0 84.0 85.0 0.0 87.0 86.0 84.0 84.0 79.0 80.0 83.0 85.0 85.0 84.0 84.0 85.0 81.0 84.0 84.0 84.0 87.0 87.0 89.0 82.0 85.0 83.0 81.0 87.0 0.0 82.0 83.0 84.0 85.0 85.0 84.0 81.0 83.0 82.0 83.0 83.0 83.0 89.0 85.0 85.0 86.0 85.0 87.0 85.0 86.0 84.0 79.0 86.0 82.0 0.0 81.0 83.0 84.0 84.0 80.0 79.0 83.0 83.0 79.0 83.0 82.0 88.0 85.0 85.0 86.0 87.0 85.0 80.0 87.0 82.0 81.0 84.0 83.0 81.0 0.0 84.0 85.0 85.0 82.0 81.0 83.0 85.0 81.0 84.0 83.0 87.0 85.0 84.0 84.0 83.0 82.0 85.0 80.0 82.0 87.0 84.0 84.0 83.0 84.0 0.0 82.0 82.0 83.0 87.0 82.0 82.0 81.0 85.0 79.0 85.0 82.0 82.0 80.0 83.0 85.0 87.0 83.0 85.0 87.0 79.0 85.0 84.0 85.0 82.0 0.0 48.0 84.0 86.0 85.0 84.0 83.0 85.0 82.0 85.0 82.0 86.0 80.0 84.0 83.0 87.0 81.0 83.0 86.0 80.0 85.0 84.0 85.0 82.0 48.0 0.0 83.0 86.0 84.0 82.0 82.0 83.0 82.0 86.0 84.0 83.0 83.0 83.0 83.0 85.0 84.0 84.0 85.0 83.0 84.0 80.0 82.0 83.0 84.0 83.0 0.0 85.0 83.0 85.0 83.0 84.0 83.0 87.0 84.0 85.0 88.0 88.0 89.0 84.0 88.0 84.0 0.0 85.0 81.0 79.0 81.0 87.0 86.0 86.0 85.0 0.0 84.0 83.0 84.0 83.0 86.0 90.0 85.0 85.0 84.0 85.0 81.0 85.0 84.0 82.0 84.0 85.0 83.0 83.0 83.0 82.0 85.0 84.0 83.0 84.0 0.0 82.0 83.0 82.0 82.0 87.0 84.0 83.0 82.0 85.0 84.0 83.0 82.0 82.0 83.0 84.0 82.0 83.0 85.0 82.0 84.0 82.0 85.0 83.0 82.0 0.0 82.0 80.0 84.0 83.0 81.0 80.0 85.0 86.0 85.0 83.0 80.0 83.0 84.0 84.0 83.0 79.0 81.0 81.0 83.0 82.0 83.0 84.0 83.0 82.0 0.0 80.0 82.0 86.0 83.0 82.0 84.0 86.0 87.0 85.0 83.0 81.0 83.0 85.0 83.0 83.0 84.0 85.0 85.0 83.0 84.0 83.0 82.0 80.0 80.0 0.0 82.0 88.0 84.0 82.0 83.0 83.0 86.0 84.0 85.0 82.0 86.0 81.0 83.0 82.0 83.0 79.0 82.0 82.0 83.0 86.0 82.0 84.0 82.0 82.0 0.0 88.0 83.0 79.0 82.0 83.0 86.0 91.0 84.0 86.0 90.0 84.0 89.0 88.0 87.0 85.0 85.0 86.0 87.0 90.0 87.0 83.0 86.0 88.0 88.0 0.0 83.0 86.0 84.0 83.0 82.0 88.0 78.0 83.0 85.0 84.0 85.0 85.0 85.0 82.0 82.0 84.0 84.0 85.0 84.0 81.0 83.0 84.0 83.0 83.0 0.0 80.0 84.0 85.0 84.0 85.0 81.0 80.0 85.0 84.0 85.0 85.0 84.0 82.0 86.0 83.0 85.0 85.0 83.0 80.0 82.0 82.0 79.0 86.0 80.0 0.0 #FASTA SCORE matrix of loop sequence - 7 11 3 6 7 5 -4 7 -2 13 10 6 6 4 8 12 11 6 - 13 7 7 6 - - 10 9 15 11 14 3 10 7 12 4 12 19 14 13 5 9 8 5 8 12 13 12 - - - 13 16 7 15 6 4 8 6 8 6 9 7 7 9 12 5 -1 12 6 10 7 - - - - 15 6 16 9 3 7 5 - 7 10 18 6 1 4 16 -2 4 7 9 8 - - - - - 12 20 9 9 13 11 3 11 14 9 12 4 7 7 4 7 11 15 12 - - - - - - 11 - 10 4 12 4 11 10 5 12 5 6 6 4 7 11 12 11 - - - - - - - 10 8 12 10 2 12 15 10 11 3 6 8 3 6 12 14 13 - - - - - - - - -3 10 -1 -7 1 4 3 - -6 -3 1 1 -3 1 3 2 - - - - - - - - - 1 12 5 9 9 4 12 13 4 4 4 7 11 9 9 - - - - - - - - - - 3 -5 3 6 1 4 -4 -1 -1 9 -1 3 7 4 - - - - - - - - - - - 5 11 11 6 13 7 6 8 5 8 12 12 11 - - - - - - - - - - - - 4 3 1 5 10 10 1 -3 10 4 5 6 - - - - - - - - - - - - - 13 8 11 4 7 8 3 6 12 13 15 - - - - - - - - - - - - - - 15 12 4 8 9 4 7 13 12 13 - - - - - - - - - - - - - - - 7 2 6 17 -1 5 8 7 8 - - - - - - - - - - - - - - - - 7 6 9 10 13 17 12 11 - - - - - - - - - - - - - - - - - 9 2 -1 12 6 4 4 - - - - - - - - - - - - - - - - - - 4 -2 11 5 8 8 - - - - - - - - - - - - - - - - - - - 1 7 10 6 8 - - - - - - - - - - - - - - - - - - - - 5 9 4 3 - - - - - - - - - - - - - - - - - - - - - 12 7 6 - - - - - - - - - - - - - - - - - - - - - - 11 12 - - - - - - - - - - - - - - - - - - - - - - - 14 - - - - - - - - - - - - - - - - - - - - - - - - #FASTA SCORE matrix of motif sequence - 48 12 8 13 13 12 -12 -12 -1 14 9 12 - 6 10 12 11 8 -7 23 6 7 8 - - 13 8 9 9 23 -5 -4 11 15 -4 17 17 18 16 1 12 - - 10 26 21 24 - - - 11 18 7 20 4 -2 10 5 17 - -1 21 7 18 12 5 -16 14 15 11 13 - - - - 21 14 18 -3 8 5 - 8 2 13 19 8 13 10 15 -7 2 - 8 14 - - - - - 8 11 23 -1 4 12 -1 8 2 14 14 -19 10 - 11 19 21 11 15 - - - - - - 5 -8 -16 -8 -7 11 -6 -3 -6 11 -9 4 3 - 14 13 7 -8 - - - - - - - 9 22 27 38 -2 29 39 15 14 2 25 3 -6 -8 11 19 18 - - - - - - - - -16 20 -6 -16 -10 -3 -2 -4 -18 -1 -2 20 -23 -11 -9 -3 - - - - - - - - - 7 28 2 8 23 1 11 5 16 -1 -5 -7 -4 6 19 - - - - - - - - - - 20 -16 21 36 20 10 -15 1 - 7 -21 -9 - 20 - - - - - - - - - - - -8 15 20 13 22 -3 18 -3 -8 -2 6 - 21 - - - - - - - - - - - - -10 -6 2 -3 23 9 8 1 19 10 -4 9 - - - - - - - - - - - - - 56 29 11 -11 -1 6 5 -7 5 22 27 - - - - - - - - - - - - - - 37 11 -7 7 -2 3 -4 3 23 31 - - - - - - - - - - - - - - - 8 -5 5 29 -7 5 11 11 24 - - - - - - - - - - - - - - - - -8 11 32 2 - 17 13 14 - - - - - - - - - - - - - - - - - -8 -2 -11 - -13 -14 -9 - - - - - - - - - - - - - - - - - - -1 3 10 17 13 19 - - - - - - - - - - - - - - - - - - - 5 - 1 -5 4 - - - - - - - - - - - - - - - - - - - - -1 9 - -1 - - - - - - - - - - - - - - - - - - - - - 19 - 8 - - - - - - - - - - - - - - - - - - - - - - 10 25 - - - - - - - - - - - - - - - - - - - - - - - 25 - - - - - - - - - - - - - - - - - - - - - - - - #FASTA SCORE matrix of global PDB chain sequence - 804 -25 -701 -58 -355 -662 -80 -441 -353 -341 -109 -57 -64 -161 -662 -275 -156 -217 -302 -169 -81 -90 -113 - - -24 -727 -71 -298 -670 -82 -436 -326 -345 -102 -70 -83 -156 -670 -269 -166 -250 -306 -157 -67 -89 -96 - - - -732 3 -288 -696 -97 -498 -350 -386 -107 -154 -101 -191 -696 -14 -200 -299 -351 -193 -102 -78 -84 - - - - -694 -306 -126 -676 -185 -330 -241 -606 -656 -642 -437 -126 -368 -423 -345 -345 -472 -916 -669 -520 - - - - - -308 -637 -53 -422 -292 -367 -53 -106 -60 -164 -637 -252 -158 -187 -278 -168 -121 -32 -58 - - - - - - -251 -259 -192 -124 -122 -166 -196 -209 -162 -251 -90 -111 -115 -67 -143 -450 -234 -181 - - - - - - - -523 -126 217 -64 -528 -565 -538 -370 4583 -321 -388 -201 -261 -463 -802 -562 -526 - - - - - - - - -407 -258 -267 -75 -9 -4 -109 -523 -250 -155 -150 -247 -99 -123 -96 -92 - - - - - - - - - -109 -133 -308 -350 -378 -264 -126 -128 -223 -207 -210 -246 -597 -371 -326 - - - - - - - - - - 37 -193 -239 -225 -95 217 -64 -168 128 -117 -183 -475 -260 -223 - - - - - - - - - - - -239 -261 -253 -164 -64 -129 -151 34 -154 -148 -457 -331 -224 - - - - - - - - - - - - -50 -50 -91 -528 -182 -124 -102 -207 107 -216 -72 -54 - - - - - - - - - - - - - 1000 -85 -565 -228 -149 -169 -238 -122 -176 -76 -72 - - - - - - - - - - - - - - -98 -538 -217 -103 -137 -220 -110 -197 -82 -63 - - - - - - - - - - - - - - - -370 -136 -88 -79 -176 -133 -316 -171 -123 - - - - - - - - - - - - - - - - -321 -388 -201 -261 -463 -802 -562 -526 - - - - - - - - - - - - - - - - - -134 -180 -120 -98 -412 -231 -166 - - - - - - - - - - - - - - - - - - -107 -158 -78 -317 -118 -97 - - - - - - - - - - - - - - - - - - - -42 -186 -356 -180 -96 - - - - - - - - - - - - - - - - - - - - -199 -458 -251 -220 - - - - - - - - - - - - - - - - - - - - - -300 -126 -46 - - - - - - - - - - - - - - - - - - - - - - -141 -195 - - - - - - - - - - - - - - - - - - - - - - - -114 - - - - - - - - - - - - - - - - - - - - - - - -