#Head information NAME 5bb0 TYPE beta-beta REPRESENTATIVE 1mlb-A_10 MEMBERS 17 CLUSTER 2 #Loop element >1mlb-A_10 tlsvTPGDSvslscra.... 5bb0_0.pdb 0 >1mam-L_10 slsaSLGDRvtiscra.... 5bb0_1.pdb 0 >1hil-A_10 sltvTAGEKvtmscts.... 5bb0_2.pdb 0 >1fdl-L_10 slsaSVGETvtitcra.... 5bb0_3.pdb 0 >1vge-L_10 slsaSVGDRvniacra.... 5bb0_4.pdb 0 >1eap-A_11 .lsaSLGGKvtitcka.... 5bb0_5.pdb 0 >1jhl-L_10 ylvaSPGETitincra.... 5bb0_6.pdb 0 >1ivl-B_10 tlsvTPGNSvsiscra.... 5bb0_7.pdb 0 >7fab-L_9 svsgAPGQRvtisct..... 5bb0_8.pdb 0 >1opg-H_11 ..lvNPGRSlklscaas... 5bb0_9.pdb 0 >1tup-A_39 kmfcQLAKTcpvqlw..... 5bb0_10.pdb 1 >1vge-H_11 .evkKPGASvkvscka.... 5bb0_11.pdb 0 >8fab-D_10 .gvvQPGRSlrlscias... 5bb0_12.pdb 0 >1flr-H_11 ..lvQPGRPmklsc...... 5bb0_13.pdb 0 >1vfa-B_11 ..lvAPSQSlsitctvs... 5bb0_14.pdb 0 >6fab-H_11 ..lvRAGSSvkmsckas... 5bb0_15.pdb 0 > 1mfa_122 .vvaRPGASvkmsckas... 5bb0_16.pdb 0 #Motif sequence TLSVTPGDSVSLSCRA.... SLSASLGDRVTISCRA.... SLTVTAGEKVTMSCTS.... SLSASVGETVTITCRA.... SLSASVGDRVNIACRA.... .LSASLGGKVTITCKA.... YLVASPGETITINCRA.... TLSVTPGNSVSISCRA.... SVSGAPGQRVTISCT..... ..LVNPGRSLKLSCAAS... KMFCQLAKTCPVQLW..... .EVKKPGASVKVSCKA.... .GVVQPGRSLRLSCIAS... ..LVQPGRPMKLSC...... ..LVAPSQSLSITCTVS... ..LVRAGSSVKMSCKAS... .VVARPGASVKMSCKAS... #Loop sequence TPGDS SLGDR TAGEK SVGET SVGDR SLGGK SPGET TPGNS APGQR NPGRS QLAKT KPGAS QPGRS QPGRP APSQS RAGSS RPGAS #Fingerprint S P G D S : : : : : : : : : : : : : E : : : : : : Q : : : : : : : R : : : : : : T : : : R : : : A : : L : : : A : : Q T : : : : : R A : G : : : : K K K V A N : N : S S P #Geometry parameters DISTANCE 7.81 ( 0.47) Vector1 ( -0.81 -0.31 -0.49) Vector2 ( 0.60 0.64 0.48) Vector3 ( -0.31 0.91 0.26) Struc diversity(A) ( 1.9 1.8 3.4 1.9 1.9) #RMSD matrix of conformation of loops (A) 0.00 0.62 0.44 0.47 0.35 0.58 0.54 0.57 0.51 1.35 1.44 0.59 1.14 0.88 0.44 0.75 0.71 0.62 0.00 0.88 0.92 0.68 0.73 0.94 0.87 0.84 1.70 1.88 0.91 1.52 1.28 0.93 1.06 1.13 0.44 0.88 0.00 0.58 0.54 0.79 0.59 0.75 0.74 1.46 1.10 0.88 1.17 1.01 0.40 0.97 0.82 0.47 0.92 0.58 0.00 0.53 0.78 0.40 0.31 0.66 1.02 1.40 0.63 0.78 0.70 0.57 0.62 0.52 0.35 0.68 0.54 0.53 0.00 0.68 0.61 0.62 0.68 1.49 1.47 0.76 1.27 1.08 0.67 0.90 0.89 0.58 0.73 0.79 0.78 0.68 0.00 0.60 0.81 0.44 1.41 1.65 0.52 1.25 0.96 0.83 0.78 0.81 0.54 0.94 0.59 0.40 0.61 0.60 0.00 0.48 0.61 1.15 1.39 0.62 0.82 0.71 0.56 0.62 0.50 0.57 0.87 0.75 0.31 0.62 0.81 0.48 0.00 0.74 0.98 1.55 0.63 0.76 0.71 0.70 0.61 0.58 0.51 0.84 0.74 0.66 0.68 0.44 0.61 0.74 0.00 1.26 1.60 0.43 1.16 0.85 0.74 0.68 0.63 1.35 1.70 1.46 1.02 1.49 1.41 1.15 0.98 1.26 0.00 1.81 1.05 0.55 0.67 1.32 0.94 0.86 1.44 1.88 1.10 1.40 1.47 1.65 1.39 1.55 1.60 1.81 0.00 1.66 1.55 1.52 1.22 1.71 1.48 0.59 0.91 0.88 0.63 0.76 0.52 0.62 0.63 0.43 1.05 1.66 0.00 0.96 0.63 0.79 0.40 0.51 1.14 1.52 1.17 0.78 1.27 1.25 0.82 0.76 1.16 0.55 1.55 0.96 0.00 0.54 1.02 0.75 0.60 0.88 1.28 1.01 0.70 1.08 0.96 0.71 0.71 0.85 0.67 1.52 0.63 0.54 0.00 0.80 0.58 0.49 0.44 0.93 0.40 0.57 0.67 0.83 0.56 0.70 0.74 1.32 1.22 0.79 1.02 0.80 0.00 0.83 0.67 0.75 1.06 0.97 0.62 0.90 0.78 0.62 0.61 0.68 0.94 1.71 0.40 0.75 0.58 0.83 0.00 0.34 0.71 1.13 0.82 0.52 0.89 0.81 0.50 0.58 0.63 0.86 1.48 0.51 0.60 0.49 0.67 0.34 0.00 #Sequence identities difference matrix of loop (%) 0.0 60.0 60.0 80.0 60.0 80.0 60.0 20.0 60.0 40.0100.0 40.0 40.0 60.0 60.0 60.0 40.0 60.0 0.0 80.0 60.0 20.0 40.0 60.0 80.0 60.0 80.0 80.0 80.0 80.0 80.0100.0 80.0 80.0 60.0 80.0 0.0 60.0 80.0 60.0 60.0 60.0 80.0 80.0100.0 80.0 80.0 80.0100.0 60.0 80.0 80.0 60.0 60.0 0.0 40.0 60.0 20.0 80.0 80.0 80.0 80.0 80.0 80.0 80.0100.0 80.0 80.0 60.0 20.0 80.0 40.0 0.0 60.0 60.0 80.0 60.0 80.0100.0 80.0 80.0 80.0100.0 80.0 80.0 80.0 40.0 60.0 60.0 60.0 0.0 60.0 80.0 80.0 80.0 80.0 80.0 80.0 80.0100.0 80.0 80.0 60.0 60.0 60.0 20.0 60.0 60.0 0.0 60.0 60.0 60.0 80.0 60.0 60.0 60.0 80.0 80.0 60.0 20.0 80.0 60.0 80.0 80.0 80.0 60.0 0.0 60.0 40.0100.0 40.0 40.0 60.0 60.0 60.0 40.0 60.0 60.0 80.0 80.0 60.0 80.0 60.0 60.0 0.0 60.0100.0 60.0 60.0 60.0 40.0 80.0 60.0 40.0 80.0 80.0 80.0 80.0 80.0 60.0 40.0 60.0 0.0100.0 40.0 20.0 40.0 60.0 60.0 40.0 100.0 80.0100.0 80.0100.0 80.0 80.0100.0100.0100.0 0.0100.0 80.0 80.0100.0100.0100.0 40.0 80.0 80.0 80.0 80.0 80.0 60.0 40.0 60.0 40.0100.0 0.0 40.0 60.0 60.0 60.0 20.0 40.0 80.0 80.0 80.0 80.0 80.0 60.0 40.0 60.0 20.0 80.0 40.0 0.0 20.0 60.0 60.0 40.0 60.0 80.0 80.0 80.0 80.0 80.0 60.0 60.0 60.0 40.0 80.0 60.0 20.0 0.0 80.0 80.0 60.0 60.0100.0100.0100.0100.0100.0 80.0 60.0 40.0 60.0100.0 60.0 60.0 80.0 0.0 80.0 60.0 60.0 80.0 60.0 80.0 80.0 80.0 80.0 60.0 80.0 60.0100.0 60.0 60.0 80.0 80.0 0.0 40.0 40.0 80.0 80.0 80.0 80.0 80.0 60.0 40.0 60.0 40.0100.0 20.0 40.0 60.0 60.0 40.0 0.0 #Sequence identities difference matrix of motif (%) 0.0 35.0 45.0 45.0 40.0 50.0 50.0 10.0 50.0 45.0 80.0 45.0 45.0 50.0 60.0 50.0 50.0 35.0 0.0 45.0 20.0 15.0 25.0 35.0 35.0 35.0 65.0 75.0 55.0 65.0 65.0 75.0 60.0 55.0 45.0 45.0 0.0 45.0 55.0 50.0 55.0 45.0 45.0 65.0 80.0 60.0 65.0 60.0 70.0 50.0 60.0 45.0 20.0 45.0 0.0 20.0 25.0 25.0 40.0 45.0 70.0 75.0 60.0 70.0 70.0 70.0 65.0 60.0 40.0 15.0 55.0 20.0 0.0 35.0 40.0 40.0 45.0 70.0 80.0 60.0 70.0 70.0 75.0 65.0 60.0 50.0 25.0 50.0 25.0 35.0 0.0 40.0 45.0 50.0 65.0 75.0 50.0 65.0 65.0 65.0 55.0 50.0 50.0 35.0 55.0 25.0 40.0 40.0 0.0 45.0 55.0 65.0 75.0 55.0 60.0 65.0 70.0 70.0 55.0 10.0 35.0 45.0 40.0 40.0 45.0 45.0 0.0 45.0 50.0 80.0 45.0 50.0 55.0 55.0 50.0 50.0 50.0 35.0 45.0 45.0 45.0 50.0 55.0 45.0 0.0 65.0 75.0 55.0 65.0 55.0 55.0 65.0 55.0 45.0 65.0 65.0 70.0 70.0 65.0 65.0 50.0 65.0 0.0 85.0 45.0 25.0 30.0 40.0 30.0 40.0 80.0 75.0 80.0 75.0 80.0 75.0 75.0 80.0 75.0 85.0 0.0 75.0 80.0 70.0 85.0 85.0 85.0 45.0 55.0 60.0 60.0 60.0 50.0 55.0 45.0 55.0 45.0 75.0 0.0 45.0 50.0 65.0 40.0 25.0 45.0 65.0 65.0 70.0 70.0 65.0 60.0 50.0 65.0 25.0 80.0 45.0 0.0 40.0 50.0 45.0 40.0 50.0 65.0 60.0 70.0 70.0 65.0 65.0 55.0 55.0 30.0 70.0 50.0 40.0 0.0 55.0 45.0 55.0 60.0 75.0 70.0 70.0 75.0 65.0 70.0 55.0 55.0 40.0 85.0 65.0 50.0 55.0 0.0 50.0 60.0 50.0 60.0 50.0 65.0 65.0 55.0 70.0 50.0 65.0 30.0 85.0 40.0 45.0 45.0 50.0 0.0 25.0 50.0 55.0 60.0 60.0 60.0 50.0 55.0 50.0 55.0 40.0 85.0 25.0 40.0 55.0 60.0 25.0 0.0 #Sequence identities difference matrix of global PDB chains (%) 0.0 21.0 25.0 20.0 38.0 23.0 67.0 57.0 60.0 75.0 85.0 76.0 73.0 76.0 85.0 76.0 72.0 21.0 0.0 25.0 18.0 36.0 19.0 68.0 71.0 60.0 76.0 85.0 77.0 75.0 76.0 86.0 75.0 70.0 25.0 25.0 0.0 25.0 40.0 27.0 71.0 70.0 57.0 74.0 84.0 75.0 75.0 76.0 86.0 74.0 68.0 20.0 18.0 25.0 0.0 36.0 21.0 68.0 71.0 59.0 76.0 87.0 76.0 75.0 76.0 83.0 76.0 69.0 38.0 36.0 40.0 36.0 0.0 40.0 64.0 70.0 58.0 73.0 85.0 72.0 72.0 75.0 83.0 76.0 68.0 23.0 19.0 27.0 21.0 40.0 0.0 69.0 72.0 60.0 76.0 85.0 76.0 76.0 77.0 83.0 74.0 72.0 67.0 68.0 71.0 68.0 64.0 69.0 0.0 37.0 79.0 83.0 85.0 84.0 84.0 86.0 69.0 83.0 81.0 57.0 71.0 70.0 71.0 70.0 72.0 37.0 0.0 79.0 85.0 87.0 83.0 82.0 84.0 73.0 82.0 83.0 60.0 60.0 57.0 59.0 58.0 60.0 79.0 79.0 0.0 74.0 82.0 71.0 71.0 74.0 83.0 72.0 68.0 75.0 76.0 74.0 76.0 73.0 76.0 83.0 85.0 74.0 0.0 81.0 44.0 36.0 29.0 74.0 29.0 80.0 85.0 85.0 84.0 87.0 85.0 85.0 85.0 87.0 82.0 81.0 0.0 84.0 83.0 81.0 84.0 82.0 85.0 76.0 77.0 75.0 76.0 72.0 76.0 84.0 83.0 71.0 44.0 84.0 0.0 24.0 46.0 76.0 40.0 77.0 73.0 75.0 75.0 75.0 72.0 76.0 84.0 82.0 71.0 36.0 83.0 24.0 0.0 37.0 72.0 46.0 79.0 76.0 76.0 76.0 76.0 75.0 77.0 86.0 84.0 74.0 29.0 81.0 46.0 37.0 0.0 75.0 38.0 80.0 85.0 86.0 86.0 83.0 83.0 83.0 69.0 73.0 83.0 74.0 84.0 76.0 72.0 75.0 0.0 75.0 81.0 76.0 75.0 74.0 76.0 76.0 74.0 83.0 82.0 72.0 29.0 82.0 40.0 46.0 38.0 75.0 0.0 77.0 72.0 70.0 68.0 69.0 68.0 72.0 81.0 83.0 68.0 80.0 85.0 77.0 79.0 80.0 81.0 77.0 0.0 #FASTA SCORE matrix of loop sequence - 13 14 11 14 5 24 30 17 21 -4 20 20 14 15 11 20 - - 13 15 29 20 10 7 12 2 3 1 1 -1 -4 4 - - - - 15 15 11 14 12 12 7 -3 5 6 5 1 11 5 - - - - 19 10 21 9 7 8 7 6 7 4 2 8 5 - - - - - 16 11 8 13 3 -1 2 2 - -3 6 1 - - - - - - 5 6 6 2 2 4 1 - -5 5 3 - - - - - - - 22 20 21 2 19 20 17 15 7 18 - - - - - - - - 17 22 -3 21 21 15 15 12 21 - - - - - - - - - 17 -4 15 17 15 21 4 14 - - - - - - - - - - 1 21 30 24 15 10 20 - - - - - - - - - - - -1 8 5 - 1 -2 - - - - - - - - - - - - 23 17 13 16 31 - - - - - - - - - - - - - 31 15 12 22 - - - - - - - - - - - - - - 9 6 16 - - - - - - - - - - - - - - - 2 12 - - - - - - - - - - - - - - - - 20 - - - - - - - - - - - - - - - - - #FASTA SCORE matrix of motif sequence - 64 56 59 60 47 59 92 47 50 -12 44 43 40 39 47 53 - - 55 77 85 73 56 61 55 22 -1 29 16 16 15 33 36 - - - 54 48 45 42 53 51 33 -9 22 28 30 28 44 35 - - - - 74 66 66 60 47 25 2 31 19 18 24 34 38 - - - - - 62 50 57 47 20 -7 27 13 14 13 32 34 - - - - - - 48 51 41 20 -3 32 14 14 17 34 39 - - - - - - - 60 44 42 -3 49 39 35 37 35 56 - - - - - - - - 50 48 -8 48 41 38 42 47 53 - - - - - - - - - 30 -12 33 26 28 42 20 40 - - - - - - - - - - -6 49 76 66 52 57 58 - - - - - - - - - - - -9 -6 1 -5 -5 -9 - - - - - - - - - - - - 47 41 30 55 73 - - - - - - - - - - - - - 66 46 50 55 - - - - - - - - - - - - - - 39 44 45 - - - - - - - - - - - - - - - 34 35 - - - - - - - - - - - - - - - - 73 - - - - - - - - - - - - - - - - - #FASTA SCORE matrix of global PDB chain sequence - 1144 1093 1177 921 1090 250 390 502 230 -85 245 258 224 -104 222 228 - - 1087 1165 918 1132 229 200 477 219 -86 245 244 208 -108 221 230 - - - 1100 885 1046 204 206 527 203 -81 227 232 214 -96 228 275 - - - - 940 1143 234 206 527 221 -68 251 261 227 -70 213 242 - - - - - 876 297 228 524 227 -84 285 268 201 -90 217 287 - - - - - - 185 169 493 213 -73 227 224 194 -98 195 194 - - - - - - - 441 17 -77 -140 -67 -84 -103 134 -92 -12 - - - - - - - - 3 -106 -170 -88 -86 -94 103 -99 -41 - - - - - - - - - 236 -28 273 284 241 -75 246 302 - - - - - - - - - - -39 860 976 1032 186 1060 93 - - - - - - - - - - - -81 -70 -65 -149 -36 -100 - - - - - - - - - - - - 1126 782 156 913 101 - - - - - - - - - - - - - 927 232 809 90 - - - - - - - - - - - - - - 178 908 92 - - - - - - - - - - - - - - - 175 78 - - - - - - - - - - - - - - - - 109 - - - - - - - - - - - - - - - - -